The Physics and Chemistry of Life

Basic Principles and Methods 1

The Central Dogma of Molecular Biology 2

From Atoms to Molecules 5

Levels of Protein Structure 7

How Mutations Change Proteins 12

Basic Molecular Functions 15

X-rays and Crystallography 18

Nuclear Magnetic Resonance 23

The First Synchrotron Experiments 24

Atomic Force Microscopy 30

Photonic Force Microscopy 33 Using Light Microscopes to Investigate

Molecules 36 Electron Microscopes and Cryo-electron

Tomography 41

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