Bibliography

Chapter 15: Initiation of Translation 221

15.1. General Principles 221

15.1.1. Significance of Initiation Stage 221

15.1.2. Prokaryotic and Eukaryotic Modes of Initiation 221

15.1.3. Components of Initiation 223

15.1.4. Steps of Initiation 223

15.2. Initiation in Prokaryotes 225

15.2.1. General Characteristics of Prokaryotic Initiation 225

15.2.2. Ribosome Binding Site and Initiation Codon 225

15.2.3. Prokaryotic Initiator tRNA 228

15.2.4. Prokaryotic Initiation Factors 230

15.2.5. Sequence of Events 231

15.3. Initiation in Eukaryotes 234

15.3.1. Characteristics of Eukaryotic mRNA 234

15.3.2. The Cap Structure and the Initiation Codons 235

15.3.3. Internal Ribosome Entry Site 237

15.3.4. Eukaryotic Initiator tRNA 240

15.3.5. Ribosomal Initiation Factors 241

15.3.6. mRNA-binding Initiation Factors 243

15.3.6.1. Cap-Binding Complex 243

15.3.6.2. RNA Helicase Complex 243

15.3.6.3. Ribosomal Complex 245

15.3.6.4. IRES-Binding Proteins 246

15.3.7. 3'- Terminal Enhancers of Initiation 247

15.3.7.2. Pseudoknot and tRNA-like Domains 247

15.3.8. Sequence of Events 250

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