I I I I

\3UCCUCC4

CAUCCAGGAGCAAAGCUAAUGGCUUUAAAU... 3' 1 1 1 1 1

^UCCUCC4

Figure 15.4. Complementary pairing of the 3'-terminal polypyrimidine cluster of ribosomal 16S RNA (lower sequences) with polypurine sequences, the so-called Shine-Dalgarno sequences, preceding the initiation codon AUG or GUG in a number of phage and bacterial mRNAs (upper sequences) (For review, see J. A. Steitz, in Ribosomes: Structure, Function, and Genetics, eds. G. Chambliss, G. R. Craven, J. Davies, K. Davis, L. Kahan, & M. Nomura, p.p. 479-495. University Park Press, Baltimore, 1980).

0 0

Post a comment