Frequency 0.642 0.142 0.217
Measures of linkage disequilibrium for G and A alleles of rs909253 and rs1800629
Coefficient of linkage disequilibrium, D = deviation of observed frequency of haplotype from expected if genotypes independent
= frequency of haplotype GA - product of frequency of the two alleles rs909253G and rs1800629A
= PGA - Prs909253G Prs1800629A
= 0.217 - (0.358 x 0.217) = 0.139 D' = observed LD relative to the maximum possible deviation given allele frequencies
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