Figure 6.12 Molecular genetics of colour vision. (A) Tandem array of red and green cone photopigment genes on chromosome Xq28. Expression of a single photopigment gene in a given photoreceptor cell is controlled by a proximal locus control region. (B) Copy number variation through non-allelic homologous recombination in intergenic region can lead to deletion of green pigment encoding gene and dichromatic vision (deuteranope). Intragenic recombination can result in green-red hybrid genes (deuteranomalous colour vision) and red-green hybrid (typically protanomalous colour vision). Modified with permission from Deeb (2005).

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