Forensic DNA profiling

Our first application of Hardy-Weinberg can be found in newspapers on a regular basis and commonly dramatized on television. A terrible crime has been committed. Left at the crime scene was a biological sample that law-enforcement authorities use to obtain a multilocus genotype or DNA profile. A suspect in the crime has been identified and subpoenaed to provide a tissue sample for DNA profiling. The DNA profiles from the suspect and from the crime scene are identical. The DNA profile is shown in Table 2.2. Should we conclude that the suspect left the biological sample found at the crime scene?

Table 2.2 Example DNA profile for three simple tandem repeat (STR) loci commonly used in human forensic cases. Locus names refer to the human chromosome (e.g. D3 means third chromosome) and chromosome region where the SRT locus is found.


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