By substituting the definition for | in equation 8.34, equation 8.35 becomes

Figure 8.14 illustrates a situation with three taxa and two divergence times. Dating events with the molecular clock requires that nucleotide divergences (adjusted for saturation) for each pair of species are estimated (KAB, KAC, and KBC) and one divergence time is known. Imagine that our goal is to determine the time of divergence for species A and B (T2) given that divergence time T1 is known. The absolute rate of substitution that occurred over the known divergence time can be estimated:

0 0

Post a comment