IT 0.50

This gives the combined departure from Hardy-Weinberg expected genotype frequencies due to the combination of non-random mating within subpopulations and divergence of allele frequencies among subpopulations. For this example, homozygosity is 40% greater or heterozygosity 60% less than would be expected in an ideal, randomly mating panmictic population with the same allele frequencies.

Problem box 4.2 Compute FIS, FST, and Ft

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