Interact box Frequency of neutral mutations in a finite population

PopGene.S2 can be used to simulate the fate of new mutations in a finite population. Click on the Mutation menu and then select Neutral Mutation. Initially, try the simulation using the default values of mutations introduced every 30 generations, a population of Ne = 10 and 200 generations. Tabulate the number of fixations and losses over several separate runs (the fate and frequency of each new mutation is independent). What are the expected number of new mutations that go to fixation and loss and how do these expectations compare with the results of the simulation? Then increase the population size to Ne = 50 and view 400 generations. How does the number of new mutations going to fixation and loss change? How does the time that new mutations segregate change?

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