Pat aPmn al Paln

t gets large, the e term approaches zero so that PG(t) approaches 1/4.

Using the continuous time equation, the probability that a nucleotide site is a G over time depending on its initial state and the rate of substitution is shown in Fig. 8.9. If the nucleotide at a site is initially a G, then PG(t) = 1 and the probability the site remains a G over time is regardless of the number of substitutions that have occurred over two generations. Since the probabilities of substitution and no substitution are independent each generation, this equation can be written in a more general form as:

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