Table

Representative Domains with Mechanical Functions for use in Protein Engineering

Representative Domains References

Serine esterase cutinase Transglutaminase sites Lysl oxidase sites

Mechanical Function

Crosslinking sites

Elasticity

Adhesion Fibrous

Association

Protease sites

Flexibility: Sequences with random coil 2° structure

Assembly

Inorganic binders

Elastin Titin Resilin Glutenin

Mussel adhesive protein Silk: Spider dragline Silk: Silkworm Keratin

Leucine zippers WW domains/polyproline repeats Calmodulin tPA and uPA sites MMP sites Plasmin sites

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