Ligand binding to macromolecules

Small molecules called ligands can attach to specific binding sites on a large molecule (called a macromolecule) such as a protein, thereby greatly altering its chemical activity. Ligands range from H+ to large organic molecules such as stearic acid (Ci7H25COOH). Metal ions such as Ca2+ can also serve as ligands. The binding sites are often metal atoms embedded in the macromolecule. Ligand binding is an equilibrium reaction treatable by modest extension of the methods of chemical thermodynamics. Binding affinity is characterized by the equilibrium (dissociation) constant for the reaction:

Getting Started With Solar

Getting Started With Solar

Do we really want the one thing that gives us its resources unconditionally to suffer even more than it is suffering now? Nature, is a part of our being from the earliest human days. We respect Nature and it gives us its bounty, but in the recent past greedy money hungry corporations have made us all so destructive, so wasteful.

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